An indoctrination virus was a human-tailored virus created to instill in those infected a sense of religious awe, and could be modified to introduce specific beliefs. One such virus was created -- presumably by the Church of Sky -- to create religious devotion towards Sky Haussmann. There were several variations and differing levels of severity with each, dependent on how one went about getting infected. For example, "Red Hand" Vasquez, a member of the Sky's Edge underworld, was required to surround himself with objects associated with Sky, otherwise he would shake uncontrollably. Despite the measures he took -- including acquiring Sleek's skull -- he still dreamed of Sky and the palm of his right hand bled on occasion. Other, more severe, strains could cause greater physical and/or psychological damage, including blindness, intense fear of the dark, and the gradual withering away of the left forearm.

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